Combined Hepatocellular-Cholangiocarcinoma in a Yellow-Headed Amazon (Amazona oratrix)

A 9-year-old male Yellow-headed Amazon (Amazona oratrix) with a history of anorexia and vomiting died of a liver tumor. The tumor consisted of neoplastic cells with hepatocellular and cholangiocellular differentiations and their intermingled areas. Neoplastic hepatocytes showed islands or trabecular...

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Autores principales: TENNAKOON, Anusha Hemamali, IZAWA, Takeshi, FUJITA, Daisuke, DENDA, Yuki, SETO, Eiko, SASAI, Hiroshi, KUWAMURA, Mitsuru, YAMATE, Jyoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2013
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942983/
https://www.ncbi.nlm.nih.gov/pubmed/23800973
http://dx.doi.org/10.1292/jvms.13-0192
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author TENNAKOON, Anusha Hemamali
IZAWA, Takeshi
FUJITA, Daisuke
DENDA, Yuki
SETO, Eiko
SASAI, Hiroshi
KUWAMURA, Mitsuru
YAMATE, Jyoji
author_facet TENNAKOON, Anusha Hemamali
IZAWA, Takeshi
FUJITA, Daisuke
DENDA, Yuki
SETO, Eiko
SASAI, Hiroshi
KUWAMURA, Mitsuru
YAMATE, Jyoji
author_sort TENNAKOON, Anusha Hemamali
collection PubMed
description A 9-year-old male Yellow-headed Amazon (Amazona oratrix) with a history of anorexia and vomiting died of a liver tumor. The tumor consisted of neoplastic cells with hepatocellular and cholangiocellular differentiations and their intermingled areas. Neoplastic hepatocytes showed islands or trabecular growth with vacuolated eosinophilic cytoplasm. Cells showing biliary differentiation formed ducts or tubules lined by cytokeratin AE1/AE3-positive epithelia, accompanied by desmoplasia consisting of myofibroblasts reacting to α-smooth muscle actin and desmin. The tumor was diagnosed as a combined hepatocellular-cholangiocarcinoma, which is very rare in the avian.
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spelling pubmed-39429832014-04-22 Combined Hepatocellular-Cholangiocarcinoma in a Yellow-Headed Amazon (Amazona oratrix) TENNAKOON, Anusha Hemamali IZAWA, Takeshi FUJITA, Daisuke DENDA, Yuki SETO, Eiko SASAI, Hiroshi KUWAMURA, Mitsuru YAMATE, Jyoji J Vet Med Sci Pathology A 9-year-old male Yellow-headed Amazon (Amazona oratrix) with a history of anorexia and vomiting died of a liver tumor. The tumor consisted of neoplastic cells with hepatocellular and cholangiocellular differentiations and their intermingled areas. Neoplastic hepatocytes showed islands or trabecular growth with vacuolated eosinophilic cytoplasm. Cells showing biliary differentiation formed ducts or tubules lined by cytokeratin AE1/AE3-positive epithelia, accompanied by desmoplasia consisting of myofibroblasts reacting to α-smooth muscle actin and desmin. The tumor was diagnosed as a combined hepatocellular-cholangiocarcinoma, which is very rare in the avian. The Japanese Society of Veterinary Science 2013-06-21 2013-11 /pmc/articles/PMC3942983/ /pubmed/23800973 http://dx.doi.org/10.1292/jvms.13-0192 Text en ©2013 The Japanese Society of Veterinary Science http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Pathology
TENNAKOON, Anusha Hemamali
IZAWA, Takeshi
FUJITA, Daisuke
DENDA, Yuki
SETO, Eiko
SASAI, Hiroshi
KUWAMURA, Mitsuru
YAMATE, Jyoji
Combined Hepatocellular-Cholangiocarcinoma in a Yellow-Headed Amazon (Amazona oratrix)
title Combined Hepatocellular-Cholangiocarcinoma in a Yellow-Headed Amazon (Amazona oratrix)
title_full Combined Hepatocellular-Cholangiocarcinoma in a Yellow-Headed Amazon (Amazona oratrix)
title_fullStr Combined Hepatocellular-Cholangiocarcinoma in a Yellow-Headed Amazon (Amazona oratrix)
title_full_unstemmed Combined Hepatocellular-Cholangiocarcinoma in a Yellow-Headed Amazon (Amazona oratrix)
title_short Combined Hepatocellular-Cholangiocarcinoma in a Yellow-Headed Amazon (Amazona oratrix)
title_sort combined hepatocellular-cholangiocarcinoma in a yellow-headed amazon (amazona oratrix)
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942983/
https://www.ncbi.nlm.nih.gov/pubmed/23800973
http://dx.doi.org/10.1292/jvms.13-0192
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