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Hepatic Encephalopathy: Early Diagnosis in Pediatric Patients With Cirrhosis

OBJECTIVE: As acute liver failure (ALF) and chronic liver disease (cirrhosis) continue to increase in prevalence, we will see more cases of hepatic encephalopathy. Primary care physician are often the first to suspect it, since they are familiar with the patient’s usual physical and mental status. T...

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Autores principales: DARA, Naghi, SAYYARI, Ali-Akbar, IMANZADEH, Farid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shahid Beheshti University of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943054/
https://www.ncbi.nlm.nih.gov/pubmed/24665321
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author DARA, Naghi
SAYYARI, Ali-Akbar
IMANZADEH, Farid
author_facet DARA, Naghi
SAYYARI, Ali-Akbar
IMANZADEH, Farid
author_sort DARA, Naghi
collection PubMed
description OBJECTIVE: As acute liver failure (ALF) and chronic liver disease (cirrhosis) continue to increase in prevalence, we will see more cases of hepatic encephalopathy. Primary care physician are often the first to suspect it, since they are familiar with the patient’s usual physical and mental status. This serious complication typically occurs in patients with severe comorbidities and needs multidisciplinary evaluation and care. Hepatic encephalopathy should be considered in any patient with acute liver failure and cirrhosis who presents with neuropsychiatric manifestations, decrease level of consciousness (coma), change of personality, intellectual and behavioral deterioration, speech and motor dysfunction. Every cirrhotic patient may be at risk; potential precipitating factors should be addressed in regular clinic visits. The encephalopathy of liver disease may be prominent, or can be present in subtle forms, such as decline of school performance, emotional outbursts, or depression. “Subtle form” of hepatic encephalopathy may not be obvious on clinical examination, but can be detected by neurophysiologic and neuropsychiatric testing.
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spelling pubmed-39430542015-03-01 Hepatic Encephalopathy: Early Diagnosis in Pediatric Patients With Cirrhosis DARA, Naghi SAYYARI, Ali-Akbar IMANZADEH, Farid Iran J Child Neurol Review Article OBJECTIVE: As acute liver failure (ALF) and chronic liver disease (cirrhosis) continue to increase in prevalence, we will see more cases of hepatic encephalopathy. Primary care physician are often the first to suspect it, since they are familiar with the patient’s usual physical and mental status. This serious complication typically occurs in patients with severe comorbidities and needs multidisciplinary evaluation and care. Hepatic encephalopathy should be considered in any patient with acute liver failure and cirrhosis who presents with neuropsychiatric manifestations, decrease level of consciousness (coma), change of personality, intellectual and behavioral deterioration, speech and motor dysfunction. Every cirrhotic patient may be at risk; potential precipitating factors should be addressed in regular clinic visits. The encephalopathy of liver disease may be prominent, or can be present in subtle forms, such as decline of school performance, emotional outbursts, or depression. “Subtle form” of hepatic encephalopathy may not be obvious on clinical examination, but can be detected by neurophysiologic and neuropsychiatric testing. Shahid Beheshti University of Medical Sciences 2014 /pmc/articles/PMC3943054/ /pubmed/24665321 Text en 2014: Iranian Journal of Child Neurology This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
DARA, Naghi
SAYYARI, Ali-Akbar
IMANZADEH, Farid
Hepatic Encephalopathy: Early Diagnosis in Pediatric Patients With Cirrhosis
title Hepatic Encephalopathy: Early Diagnosis in Pediatric Patients With Cirrhosis
title_full Hepatic Encephalopathy: Early Diagnosis in Pediatric Patients With Cirrhosis
title_fullStr Hepatic Encephalopathy: Early Diagnosis in Pediatric Patients With Cirrhosis
title_full_unstemmed Hepatic Encephalopathy: Early Diagnosis in Pediatric Patients With Cirrhosis
title_short Hepatic Encephalopathy: Early Diagnosis in Pediatric Patients With Cirrhosis
title_sort hepatic encephalopathy: early diagnosis in pediatric patients with cirrhosis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943054/
https://www.ncbi.nlm.nih.gov/pubmed/24665321
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