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Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics

In the recent past, the design and synthesis of peptide mimics (peptidomimetics) has received much attention. This because they have shown in many cases enhanced pharmacological properties over their natural peptide analogues. In particular, the incorporation of cyclic constructs into peptides is of...

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Detalles Bibliográficos
Autores principales: Koopmanschap, Gijs, Ruijter, Eelco, Orru, Romano VA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943360/
https://www.ncbi.nlm.nih.gov/pubmed/24605172
http://dx.doi.org/10.3762/bjoc.10.50