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Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae
This study investigated the biological activities of five benthic marine algae collected from Northeastern Region of Brazil. The tested activities included larvicidal activity against Aedes aegypti, molluscicidal activity against Biomphalaria glabrata, and toxicity against Artemia salina. Extracts o...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943412/ https://www.ncbi.nlm.nih.gov/pubmed/24688787 http://dx.doi.org/10.1155/2014/501328 |
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author | Guedes, Elíca Amara Cecília de Carvalho, Cenira M. Ribeiro Junior, Karlos Antonio Lisboa Lisboa Ribeiro, Thyago Fernando de Barros, Lurdiana Dayse de Lima, Maria Raquel Ferreira Prado Moura, Flávia de Barros Goulart Sant'Ana, Antônio Euzebio |
author_facet | Guedes, Elíca Amara Cecília de Carvalho, Cenira M. Ribeiro Junior, Karlos Antonio Lisboa Lisboa Ribeiro, Thyago Fernando de Barros, Lurdiana Dayse de Lima, Maria Raquel Ferreira Prado Moura, Flávia de Barros Goulart Sant'Ana, Antônio Euzebio |
author_sort | Guedes, Elíca Amara Cecília |
collection | PubMed |
description | This study investigated the biological activities of five benthic marine algae collected from Northeastern Region of Brazil. The tested activities included larvicidal activity against Aedes aegypti, molluscicidal activity against Biomphalaria glabrata, and toxicity against Artemia salina. Extracts of Ulva lactuca (Chlorophyta), Padina gymnospora, Sargassum vulgare (Phaeophyta), Hypnea musciformis, and Digenea simplex (Rhodophyta) were prepared using different solvents of increasing polarity, including dichloromethane, methanol, ethanol, and water. Of the extracts screened, the dichloromethane extracts of H. musciformis and P. gymnospora exhibited the highest activities and were subjected to bioassay-guided fractionation in hexane and chloroform. The chloroform fractions of the P. gymnospora and H. musciformis extracts showed molluscicidal activity at values below 40 μg·mL(−1) (11.1460 μg·mL(−1) and 25.8689 μg·mL(−1), resp.), and the chloroform and hexane fractions of P. gymnospora showed larvicidal activity at values below 40 μg·mL(−1) (29.018 μg·mL(−1) and 17.230 μg·mL(−1), resp.). The crude extracts were not toxic to A. salina, whereas the chloroform and hexane fractions of P. gymnospora (788.277 μg·mL(−1) and 706.990 μg·mL(−1)) showed moderate toxicity, indicating that the toxic compounds present in these algae are nonpolar. |
format | Online Article Text |
id | pubmed-3943412 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-39434122014-03-31 Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae Guedes, Elíca Amara Cecília de Carvalho, Cenira M. Ribeiro Junior, Karlos Antonio Lisboa Lisboa Ribeiro, Thyago Fernando de Barros, Lurdiana Dayse de Lima, Maria Raquel Ferreira Prado Moura, Flávia de Barros Goulart Sant'Ana, Antônio Euzebio J Parasitol Res Research Article This study investigated the biological activities of five benthic marine algae collected from Northeastern Region of Brazil. The tested activities included larvicidal activity against Aedes aegypti, molluscicidal activity against Biomphalaria glabrata, and toxicity against Artemia salina. Extracts of Ulva lactuca (Chlorophyta), Padina gymnospora, Sargassum vulgare (Phaeophyta), Hypnea musciformis, and Digenea simplex (Rhodophyta) were prepared using different solvents of increasing polarity, including dichloromethane, methanol, ethanol, and water. Of the extracts screened, the dichloromethane extracts of H. musciformis and P. gymnospora exhibited the highest activities and were subjected to bioassay-guided fractionation in hexane and chloroform. The chloroform fractions of the P. gymnospora and H. musciformis extracts showed molluscicidal activity at values below 40 μg·mL(−1) (11.1460 μg·mL(−1) and 25.8689 μg·mL(−1), resp.), and the chloroform and hexane fractions of P. gymnospora showed larvicidal activity at values below 40 μg·mL(−1) (29.018 μg·mL(−1) and 17.230 μg·mL(−1), resp.). The crude extracts were not toxic to A. salina, whereas the chloroform and hexane fractions of P. gymnospora (788.277 μg·mL(−1) and 706.990 μg·mL(−1)) showed moderate toxicity, indicating that the toxic compounds present in these algae are nonpolar. Hindawi Publishing Corporation 2014 2014-02-13 /pmc/articles/PMC3943412/ /pubmed/24688787 http://dx.doi.org/10.1155/2014/501328 Text en Copyright © 2014 Elíca Amara Cecília Guedes et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Guedes, Elíca Amara Cecília de Carvalho, Cenira M. Ribeiro Junior, Karlos Antonio Lisboa Lisboa Ribeiro, Thyago Fernando de Barros, Lurdiana Dayse de Lima, Maria Raquel Ferreira Prado Moura, Flávia de Barros Goulart Sant'Ana, Antônio Euzebio Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae |
title | Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae |
title_full | Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae |
title_fullStr | Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae |
title_full_unstemmed | Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae |
title_short | Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae |
title_sort | larvicidal activity against aedes aegypti and molluscicidal activity against biomphalaria glabrata of brazilian marine algae |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943412/ https://www.ncbi.nlm.nih.gov/pubmed/24688787 http://dx.doi.org/10.1155/2014/501328 |
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