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Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae

This study investigated the biological activities of five benthic marine algae collected from Northeastern Region of Brazil. The tested activities included larvicidal activity against Aedes aegypti, molluscicidal activity against Biomphalaria glabrata, and toxicity against Artemia salina. Extracts o...

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Autores principales: Guedes, Elíca Amara Cecília, de Carvalho, Cenira M., Ribeiro Junior, Karlos Antonio Lisboa, Lisboa Ribeiro, Thyago Fernando, de Barros, Lurdiana Dayse, de Lima, Maria Raquel Ferreira, Prado Moura, Flávia de Barros, Goulart Sant'Ana, Antônio Euzebio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943412/
https://www.ncbi.nlm.nih.gov/pubmed/24688787
http://dx.doi.org/10.1155/2014/501328
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author Guedes, Elíca Amara Cecília
de Carvalho, Cenira M.
Ribeiro Junior, Karlos Antonio Lisboa
Lisboa Ribeiro, Thyago Fernando
de Barros, Lurdiana Dayse
de Lima, Maria Raquel Ferreira
Prado Moura, Flávia de Barros
Goulart Sant'Ana, Antônio Euzebio
author_facet Guedes, Elíca Amara Cecília
de Carvalho, Cenira M.
Ribeiro Junior, Karlos Antonio Lisboa
Lisboa Ribeiro, Thyago Fernando
de Barros, Lurdiana Dayse
de Lima, Maria Raquel Ferreira
Prado Moura, Flávia de Barros
Goulart Sant'Ana, Antônio Euzebio
author_sort Guedes, Elíca Amara Cecília
collection PubMed
description This study investigated the biological activities of five benthic marine algae collected from Northeastern Region of Brazil. The tested activities included larvicidal activity against Aedes aegypti, molluscicidal activity against Biomphalaria glabrata, and toxicity against Artemia salina. Extracts of Ulva lactuca (Chlorophyta), Padina gymnospora, Sargassum vulgare (Phaeophyta), Hypnea musciformis, and Digenea simplex (Rhodophyta) were prepared using different solvents of increasing polarity, including dichloromethane, methanol, ethanol, and water. Of the extracts screened, the dichloromethane extracts of H. musciformis and P. gymnospora exhibited the highest activities and were subjected to bioassay-guided fractionation in hexane and chloroform. The chloroform fractions of the P. gymnospora and H. musciformis extracts showed molluscicidal activity at values below 40 μg·mL(−1) (11.1460 μg·mL(−1) and 25.8689 μg·mL(−1), resp.), and the chloroform and hexane fractions of P. gymnospora showed larvicidal activity at values below 40 μg·mL(−1) (29.018 μg·mL(−1) and 17.230 μg·mL(−1), resp.). The crude extracts were not toxic to A. salina, whereas the chloroform and hexane fractions of P. gymnospora (788.277 μg·mL(−1) and 706.990 μg·mL(−1)) showed moderate toxicity, indicating that the toxic compounds present in these algae are nonpolar.
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spelling pubmed-39434122014-03-31 Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae Guedes, Elíca Amara Cecília de Carvalho, Cenira M. Ribeiro Junior, Karlos Antonio Lisboa Lisboa Ribeiro, Thyago Fernando de Barros, Lurdiana Dayse de Lima, Maria Raquel Ferreira Prado Moura, Flávia de Barros Goulart Sant'Ana, Antônio Euzebio J Parasitol Res Research Article This study investigated the biological activities of five benthic marine algae collected from Northeastern Region of Brazil. The tested activities included larvicidal activity against Aedes aegypti, molluscicidal activity against Biomphalaria glabrata, and toxicity against Artemia salina. Extracts of Ulva lactuca (Chlorophyta), Padina gymnospora, Sargassum vulgare (Phaeophyta), Hypnea musciformis, and Digenea simplex (Rhodophyta) were prepared using different solvents of increasing polarity, including dichloromethane, methanol, ethanol, and water. Of the extracts screened, the dichloromethane extracts of H. musciformis and P. gymnospora exhibited the highest activities and were subjected to bioassay-guided fractionation in hexane and chloroform. The chloroform fractions of the P. gymnospora and H. musciformis extracts showed molluscicidal activity at values below 40 μg·mL(−1) (11.1460 μg·mL(−1) and 25.8689 μg·mL(−1), resp.), and the chloroform and hexane fractions of P. gymnospora showed larvicidal activity at values below 40 μg·mL(−1) (29.018 μg·mL(−1) and 17.230 μg·mL(−1), resp.). The crude extracts were not toxic to A. salina, whereas the chloroform and hexane fractions of P. gymnospora (788.277 μg·mL(−1) and 706.990 μg·mL(−1)) showed moderate toxicity, indicating that the toxic compounds present in these algae are nonpolar. Hindawi Publishing Corporation 2014 2014-02-13 /pmc/articles/PMC3943412/ /pubmed/24688787 http://dx.doi.org/10.1155/2014/501328 Text en Copyright © 2014 Elíca Amara Cecília Guedes et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Guedes, Elíca Amara Cecília
de Carvalho, Cenira M.
Ribeiro Junior, Karlos Antonio Lisboa
Lisboa Ribeiro, Thyago Fernando
de Barros, Lurdiana Dayse
de Lima, Maria Raquel Ferreira
Prado Moura, Flávia de Barros
Goulart Sant'Ana, Antônio Euzebio
Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae
title Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae
title_full Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae
title_fullStr Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae
title_full_unstemmed Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae
title_short Larvicidal Activity against Aedes aegypti and Molluscicidal Activity against Biomphalaria glabrata of Brazilian Marine Algae
title_sort larvicidal activity against aedes aegypti and molluscicidal activity against biomphalaria glabrata of brazilian marine algae
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943412/
https://www.ncbi.nlm.nih.gov/pubmed/24688787
http://dx.doi.org/10.1155/2014/501328
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