Simple two-step synthesis of 2,4-disubstituted pyrroles and 3,5-disubstituted pyrrole-2-carbonitriles from enones

The cyclocondensation of enones with aminoacetonitrile furnishes 3,4-dihydro-2H-pyrrole-2-carbonitriles which can be readily converted to 2,4-disubstituted pyrroles by microwave-induced dehydrocyanation. Alternatively, oxidation of the intermediates produces 3,5-disubstituted pyrrole-2-carbonitriles...

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Detalles Bibliográficos
Autores principales: Kucukdisli, Murat, Ferenc, Dorota, Heinz, Marcel, Wiebe, Christine, Opatz, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943414/
https://www.ncbi.nlm.nih.gov/pubmed/24605166
http://dx.doi.org/10.3762/bjoc.10.44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943414/
https://www.ncbi.nlm.nih.gov/pubmed/24605166
http://dx.doi.org/10.3762/bjoc.10.44

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