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Epstein-Barr virus and telomerase: from cell immortalization to therapy
Overcoming cellular senescence is strictly required for virus-driven tumors, including those associated with Epstein-Barr virus (EBV). This critical step is successfully accomplished by EBV through TERT expression and telomerase activation in infected cells. We herein review the complex interplay be...
Autores principales: | Dolcetti, Riccardo, Giunco, Silvia, Dal Col, Jessica, Celeghin, Andrea, Mastorci, Katy, De Rossi, Anita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943417/ https://www.ncbi.nlm.nih.gov/pubmed/24572088 http://dx.doi.org/10.1186/1750-9378-9-8 |
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