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LBSapSal-vaccinated dogs exhibit increased circulating T-lymphocyte subsets (CD4(+) and CD8(+)) as well as a reduction of parasitism after challenge with Leishmania infantum plus salivary gland of Lutzomyia longipalpis
BACKGROUND: The development of a protective vaccine against canine visceral leishmaniasis (CVL) is an alternative approach for interrupting the domestic cycle of Leishmania infantum. Given the importance of sand fly salivary proteins as potent immunogens obligatorily co-deposited during transmission...
Autores principales: | Aguiar-Soares, Rodrigo Dian de Oliveira, Roatt, Bruno Mendes, Ker, Henrique Gama, Moreira, Nádia das Dores, Mathias, Fernando Augusto Siqueira, Cardoso, Jamille Mirelle de Oliveira, Gontijo, Nelder Figueiredo, Bruna-Romero, Oscar, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis, Corrêa-Oliveira, Rodrigo, Giunchetti, Rodolfo Cordeiro, Reis, Alexandre Barbosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943450/ https://www.ncbi.nlm.nih.gov/pubmed/24507702 http://dx.doi.org/10.1186/1756-3305-7-61 |
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