Intermittent or Sustained Systemic Inflammation (ISSI) and the Preterm Brain

Exposure to perinatal infection and inflammation is associated with an increased risk for neonatal brain damage and developmental disabilities. In this integrated mechanism review, we discuss evidence in support of the contention that the preterm newborn is capable of intermittent or sustained syste...

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Detalles Bibliográficos
Autores principales: Dammann, Olaf, Leviton, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943674/
https://www.ncbi.nlm.nih.gov/pubmed/24429547
http://dx.doi.org/10.1038/pr.2013.238
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author Dammann, Olaf
Leviton, Alan
author_facet Dammann, Olaf
Leviton, Alan
author_sort Dammann, Olaf
collection PubMed
description Exposure to perinatal infection and inflammation is associated with an increased risk for neonatal brain damage and developmental disabilities. In this integrated mechanism review, we discuss evidence in support of the contention that the preterm newborn is capable of intermittent or sustained systemic inflammation (ISSI), which appears to contribute more to adverse neurodevelopmental outcomes in preterm infants than does shorter duration inflammation.
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spelling pubmed-39436742014-09-01 Intermittent or Sustained Systemic Inflammation (ISSI) and the Preterm Brain Dammann, Olaf Leviton, Alan Pediatr Res Article Exposure to perinatal infection and inflammation is associated with an increased risk for neonatal brain damage and developmental disabilities. In this integrated mechanism review, we discuss evidence in support of the contention that the preterm newborn is capable of intermittent or sustained systemic inflammation (ISSI), which appears to contribute more to adverse neurodevelopmental outcomes in preterm infants than does shorter duration inflammation. 2013-12-12 2014-03 /pmc/articles/PMC3943674/ /pubmed/24429547 http://dx.doi.org/10.1038/pr.2013.238 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Dammann, Olaf
Leviton, Alan
Intermittent or Sustained Systemic Inflammation (ISSI) and the Preterm Brain
title Intermittent or Sustained Systemic Inflammation (ISSI) and the Preterm Brain
title_full Intermittent or Sustained Systemic Inflammation (ISSI) and the Preterm Brain
title_fullStr Intermittent or Sustained Systemic Inflammation (ISSI) and the Preterm Brain
title_full_unstemmed Intermittent or Sustained Systemic Inflammation (ISSI) and the Preterm Brain
title_short Intermittent or Sustained Systemic Inflammation (ISSI) and the Preterm Brain
title_sort intermittent or sustained systemic inflammation (issi) and the preterm brain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943674/
https://www.ncbi.nlm.nih.gov/pubmed/24429547
http://dx.doi.org/10.1038/pr.2013.238
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