A Functional Ser326Cys Polymorphism in hOGG1 Is Associated with Noise-Induced Hearing Loss in a Chinese Population

DNA damage to cochlear hair cells caused by 8-oxoguanine (8-oxoG) is essential for the development of noise-induced hearing loss (NIHL). Human 8-oxoG DNA glycosylase1 (hOGG1) is a key enzyme in the base excision repair (BER) pathway that eliminates 8-oxoG. Many epidemiological and functional studies...

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Detalles Bibliográficos
Autores principales: Shen, Huanxi, Cao, Jinglian, Hong, Zhiqiang, Liu, Kai, Shi, Jian, Ding, Lu, Zhang, Hengdong, Du, Cheng, Li, Qian, Zhang, Zhengdong, Zhu, Baoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943766/
https://www.ncbi.nlm.nih.gov/pubmed/24599382
http://dx.doi.org/10.1371/journal.pone.0089662

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