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Exposure of Allium cepa Root Cells to Zidovudine or Nevirapine Induces Cytogenotoxic Changes

Antiretroviral drugs have proved useful in the clinical management of HIV-infected persons, though there are concerns about the effects of exposure to these DNA-reactive drugs. We investigated the potential of the plant model Allium cepa root tip assay to demonstrate the cytogenotoxicity of zidovudi...

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Detalles Bibliográficos
Autores principales:	Onwuamah, Chika K., Ekama, Sabdat O., Audu, Rosemary A., Ezechi, Oliver C., Poirier, Miriam C., Odeigah, Peter G C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943917/ https://www.ncbi.nlm.nih.gov/pubmed/24599327 http://dx.doi.org/10.1371/journal.pone.0090296

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