Cargando…

Exposure of Allium cepa Root Cells to Zidovudine or Nevirapine Induces Cytogenotoxic Changes

Antiretroviral drugs have proved useful in the clinical management of HIV-infected persons, though there are concerns about the effects of exposure to these DNA-reactive drugs. We investigated the potential of the plant model Allium cepa root tip assay to demonstrate the cytogenotoxicity of zidovudi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Onwuamah, Chika K., Ekama, Sabdat O., Audu, Rosemary A., Ezechi, Oliver C., Poirier, Miriam C., Odeigah, Peter G C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943917/ https://www.ncbi.nlm.nih.gov/pubmed/24599327 http://dx.doi.org/10.1371/journal.pone.0090296

Ejemplares similares

Foetal Loss and Enhanced Fertility Observed in Mice Treated with Zidovudine or Nevirapine
por: Onwuamah, Chika K., et al.
Publicado: (2014)

Assessment of Cytogenotoxicity of Plastic Industrial Effluent Using Allium cepa Root Tip Cells
por: Mohammed, Jibril Sani, et al.
Publicado: (2023)

Allium cepa Bio Assay to Assess the Water and Sediment Cytogenotoxicity in a Tropical Stream Subjected to Multiple Point and Nonpoint Source Pollutants
por: Wijeyaratne, W. M. Dimuthu Nilmini, et al.
Publicado: (2019)

Cytogenetic effects of silver and gold nanoparticles on Allium cepa roots
por: Debnath, Priyanka, et al.
Publicado: (2018)

Phytotoxic Effects of Polystyrene and Polymethyl Methacrylate Microplastics on Allium cepa Roots
por: Biba, Renata, et al.
Publicado: (2023)

Actin in the preprophase band of Allium cepa
Publicado: (1987)

Intrinsic Replication Competences of HIV Strains After Zidovudine/Lamivudine/Nevirapine Treatment in the Philippines
por: Kageyama, Seiji, et al.
Publicado: (2019)

Comparative Dissection of Three Giant Genomes: Allium cepa, Allium sativum, and Allium ursinum
por: Peška, Vratislav, et al.
Publicado: (2019)

Immunological characterization of onion (Allium cepa) allergy
por: Albanesi, Marcello, et al.
Publicado: (2019)

Genotoxicity of Euphorbia hirta: An Allium cepa Assay
por: Ping, Kwan Yuet, et al.
Publicado: (2012)

Efecto inhibitorio de Allium Cepa y Allium Sativum sobre cepas de Escherichia Coli y Salmonella Enteritidis
por: Sánchez Aguilar, María Antonia
Publicado: (2013)

Effect of Aqueous Allium cepa and Ixora brachiata Root Extract on Leishmania major Promastigotes
por: Sadeghi-Nejad, Batool, et al.
Publicado: (2014)

Chromosomal and Nuclear Alterations in Root Tip Cells of Allium Cepa L. Induced by Alprazolam
por: Nefic, Hilada, et al.
Publicado: (2013)

Artemisinin-Based Combination Therapy Depressed Mitosis and Induced Chromosome Aberration in Onion Root Cells
por: Raji, J. I., et al.
Publicado: (2018)

In vitro cytogenotoxic evaluation of sertraline
por: Istifli, Erman Salih, et al.
Publicado: (2018)

N348I in the Connection Domain of HIV-1 Reverse Transcriptase Confers Zidovudine and Nevirapine Resistance
por: Yap, Soo-Huey, et al.
Publicado: (2007)

In Vivo Genotoxicity Assessment of Titanium Dioxide Nanoparticles by Allium cepa Root Tip Assay at High Exposure Concentrations
por: Pakrashi, Sunandan, et al.
Publicado: (2014)

Exposure to 2100 MHz electromagnetic field radiations induces reactive oxygen species generation in Allium cepa roots
por: Chandel, Shikha, et al.
Publicado: (2017)

Testosterone in Males as Enhanced by Onion (Allium Cepa L.)
por: Banihani, Saleem Ali
Publicado: (2019)

Identification and characterization of abundant repetitive sequences in Allium cepa
por: Fu, Jiaping, et al.
Publicado: (2019)

Effects of Lead on the Morphology and Structure of the Nucleolus in the Root Tip Meristematic Cells of Allium cepa L.
por: Jiang, Ze, et al.
Publicado: (2014)

Changes in radical scavenging activity of normal, endoreduplicated and depolyploid root tip cells of Allium cepa
por: Tank, Jigna G., et al.
Publicado: (2017)

Cytotoxicity and genotoxicity effects of water boiled in aluminum vessels on Allium cepa root tip cells
por: Zendehboodi, Zahra
Publicado: (2018)

Butylated hydroxytoluene and Butylated hydroxyanisole induced cyto-genotoxicity in root cells of Allium cepa L.
por: Pandey, Himadri, et al.
Publicado: (2021)

Mucoadhesive Microspheres of Maraviroc and Tenofovir Designed for Pre-Exposure Prophylaxis of HIV-1: An in vitro Assessment of the Effect on Vaginal Lactic Acid Bacteria Microflora
por: Ekama, Sabdat O, et al.
Publicado: (2021)

Enzyme Responsive Vaginal Microbicide Gels Containing Maraviroc and Tenofovir Microspheres Designed for Acid Phosphatase-Triggered Release for Pre-Exposure Prophylaxis of HIV-1: A Comparative Analysis of a Bigel and Thermosensitive Gel
por: Ekama, Sabdat Ozichu, et al.
Publicado: (2021)

Correction: In Vivo Genotoxicity Assessment of Titanium Dioxide Nanoparticles by Allium cepa Root Tip Assay at High Exposure Concentrations
Publicado: (2014)

A comparative profile of methanol extracts of Allium cepa and Allium sativum in diabetic neuropathy in mice
por: Bhanot, Abhishek, et al.
Publicado: (2010)

The effect of pre-incubation of Allium cepa L. roots in the ATH-rich extract on Pb uptake and localization
por: Glińska, Sława, et al.
Publicado: (2012)

Assessment of malathion toxicity on cytophysiological activity, DNA damage and antioxidant enzymes in root of Allium cepa model
por: Srivastava, Akhileshwar Kumar, et al.
Publicado: (2020)

Mechanism of Viral Suppression among HIV Elite Controllers and Long-Term Nonprogressors in Nigeria and South Africa
por: Ahmed, Rahaman Ademolu, et al.
Publicado: (2022)

Molecular and Functional Characterization of FLOWERING LOCUS T Homologs in Allium cepa
por: Manoharan, Ranjith Kumar, et al.
Publicado: (2016)

Insights from the first genome assembly of Onion (Allium cepa)
por: Finkers, Richard, et al.
Publicado: (2021)

Screening of Onion (Allium cepa L.) Genotypes for Waterlogging Tolerance
por: Gedam, Pranjali A., et al.
Publicado: (2022)

Reduced Genotoxicity of Gold Nanoparticles With Protein Corona in Allium cepa
por: Arya, Sagar S., et al.
Publicado: (2022)

Characterization of the Biochemical Potential of Moroccan Onions (Allium cepa L.)
por: Brahimi, Amal, et al.
Publicado: (2022)

Genome Dominance in Allium Hybrids (A. cepa × A. roylei)
por: Kopecký, David, et al.
Publicado: (2022)

Anthracnose of Onion (Allium cepa L.): A Twister Disease
por: Dutta, Ram, et al.
Publicado: (2022)

Effects of the flower extract of Ixora coccinea Linn. On the meristematic cells of Allium Cepa
por: Latha, P.G., et al.
Publicado: (1998)

Superior Effectiveness of Zidovudine Compared With Tenofovir When Combined With Nevirapine-based Antiretroviral Therapy in a Large Nigerian Cohort
por: Scarsi, Kimberly K., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_86989ce4shd6tn4hec43ivcamo