Selective Inhibition of PI3K/Akt/mTOR Signaling Pathway Regulates Autophagy of Macrophage and Vulnerability of Atherosclerotic Plaque

Macrophage infiltration contributes to the instability of atherosclerotic plaques. In the present study, we investigated whether selective inhibition of PI3K/Akt/mTOR signaling pathway can enhance the stability of atherosclerotic plaques by activation of macrophage autophagy. In vitro study, selecti...

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Detalles Bibliográficos
Autores principales: Zhai, Chungang, Cheng, Jing, Mujahid, Haroon, Wang, Hefeng, Kong, Jing, Yin, Yue, Li, Jifu, Zhang, Yun, Ji, Xiaoping, Chen, Wenqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944201/
https://www.ncbi.nlm.nih.gov/pubmed/24599185
http://dx.doi.org/10.1371/journal.pone.0090563

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