A new manganese-mediated, cobalt-catalyzed three-component synthesis of (diarylmethyl)sulfonamides

The synthesis of (diarylmethyl)sulfonamides and related compounds by a new manganese-mediated, cobalt-catalyzed three-component reaction between sulfonamides, carbonyl compounds and organic bromides is described. This organometallic Mannich-like process allows the formation of the coupling products...

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Detalles Bibliográficos
Autores principales: Pignon, Antoine, Le Gall, Erwan, Martens, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944212/
https://www.ncbi.nlm.nih.gov/pubmed/24605162
http://dx.doi.org/10.3762/bjoc.10.39
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author Pignon, Antoine
Le Gall, Erwan
Martens, Thierry
author_facet Pignon, Antoine
Le Gall, Erwan
Martens, Thierry
author_sort Pignon, Antoine
collection PubMed
description The synthesis of (diarylmethyl)sulfonamides and related compounds by a new manganese-mediated, cobalt-catalyzed three-component reaction between sulfonamides, carbonyl compounds and organic bromides is described. This organometallic Mannich-like process allows the formation of the coupling products within minutes at room temperature. A possible mechanism, emphasizing the crucial role of manganese is proposed.
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spelling pubmed-39442122014-03-06 A new manganese-mediated, cobalt-catalyzed three-component synthesis of (diarylmethyl)sulfonamides Pignon, Antoine Le Gall, Erwan Martens, Thierry Beilstein J Org Chem Letter The synthesis of (diarylmethyl)sulfonamides and related compounds by a new manganese-mediated, cobalt-catalyzed three-component reaction between sulfonamides, carbonyl compounds and organic bromides is described. This organometallic Mannich-like process allows the formation of the coupling products within minutes at room temperature. A possible mechanism, emphasizing the crucial role of manganese is proposed. Beilstein-Institut 2014-02-17 /pmc/articles/PMC3944212/ /pubmed/24605162 http://dx.doi.org/10.3762/bjoc.10.39 Text en Copyright © 2014, Pignon et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Letter
Pignon, Antoine
Le Gall, Erwan
Martens, Thierry
A new manganese-mediated, cobalt-catalyzed three-component synthesis of (diarylmethyl)sulfonamides
title A new manganese-mediated, cobalt-catalyzed three-component synthesis of (diarylmethyl)sulfonamides
title_full A new manganese-mediated, cobalt-catalyzed three-component synthesis of (diarylmethyl)sulfonamides
title_fullStr A new manganese-mediated, cobalt-catalyzed three-component synthesis of (diarylmethyl)sulfonamides
title_full_unstemmed A new manganese-mediated, cobalt-catalyzed three-component synthesis of (diarylmethyl)sulfonamides
title_short A new manganese-mediated, cobalt-catalyzed three-component synthesis of (diarylmethyl)sulfonamides
title_sort new manganese-mediated, cobalt-catalyzed three-component synthesis of (diarylmethyl)sulfonamides
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944212/
https://www.ncbi.nlm.nih.gov/pubmed/24605162
http://dx.doi.org/10.3762/bjoc.10.39
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