Cargando…

Early and sustained altered expression of aging-related genes in young 3xTg-AD mice

Alzheimer's disease (AD) is a multifactorial neurological condition associated with a genetic profile that is still not completely understood. In this study, using a whole gene microarray approach, we investigated age-dependent gene expression profile changes occurring in the hippocampus of you...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gatta, V, D'Aurora, M, Granzotto, A, Stuppia, L, Sensi, S L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944230/ https://www.ncbi.nlm.nih.gov/pubmed/24525730 http://dx.doi.org/10.1038/cddis.2014.11

Ejemplares similares

Age-Dependent Modifications of AMPA Receptor Subunit Expression Levels and Related Cognitive Effects in 3xTg-AD Mice
por: Cantanelli, Pamela, et al.
Publicado: (2014)

Dopaminergic dysfunction in the 3xTg-AD mice model of Alzheimer’s disease
por: Gloria, Yesica, et al.
Publicado: (2021)

Effects of Dietary Supplementation of Carnosine on Mitochondrial Dysfunction, Amyloid Pathology, and Cognitive Deficits in 3xTg-AD Mice
por: Corona, Carlo, et al.
Publicado: (2011)

Gender-Specific Neuroimmunoendocrine Response to Treadmill Exercise in 3xTg-AD Mice
por: Giménez-Llort, Lydia, et al.
Publicado: (2010)

Olfactory dysfunction in the 3xTg-AD model of Alzheimer’s disease
por: Mitrano, Darlene A., et al.
Publicado: (2021)

Sex-dependent alterations in the physiology of entorhinal cortex neurons in old heterozygous 3xTg-AD mice
por: Arsenault, Dany, et al.
Publicado: (2020)

Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunction
por: Corona, C, et al.
Publicado: (2010)

Intranasal insulin prevents anesthesia-induced hyperphosphorylation of tau in 3xTg-AD mice
por: Chen, Yanxing, et al.
Publicado: (2014)

Temporal and regional progression of Alzheimer’s disease‐like pathology in 3xTg‐AD mice
por: Belfiore, Ramona, et al.
Publicado: (2018)

Neuroprotective Effects of Probiotic-Supplemented Diet on Cognitive Behavior of 3xTg-AD Mice
por: Tan, Chenxi, et al.
Publicado: (2022)

Supragranular Pyramidal Cells Exhibit Early Metabolic Alterations in the 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Piquet, Juliette, et al.
Publicado: (2018)

Effects of long-term treatment with pioglitazone on cognition and glucose metabolism of PS1-KI, 3xTg-AD, and wild-type mice
por: Masciopinto, F, et al.
Publicado: (2012)

Exenatide promotes cognitive enhancement and positive brain metabolic changes in PS1-KI mice but has no effects in 3xTg-AD animals
por: Bomba, M, et al.
Publicado: (2013)

Impaired Spatial Reorientation in the 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Stimmell, Alina C., et al.
Publicado: (2019)

Treatment of Alzheimer's Disease with Anti-Homocysteic Acid Antibody in 3xTg-AD Male Mice
por: Hasegawa, Tohru, et al.
Publicado: (2010)

DHA Improves Cognition and Prevents Dysfunction of Entorhinal Cortex Neurons in 3xTg-AD Mice
por: Arsenault, Dany, et al.
Publicado: (2011)

Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice
por: Van der Jeugd, Ann, et al.
Publicado: (2018)

Enhanced susceptibility of triple transgenic Alzheimer’s disease (3xTg-AD) mice to acute infection
por: Montacute, Rebecca, et al.
Publicado: (2017)

Retracted: Neuroprotective Effects of Probiotic-Supplemented Diet on Cognitive Behavior of 3xTg-AD Mice
por: Engineering, Journal of Healthcare
Publicado: (2023)

Endogenous Amyloid-formed Ca(2+)-permeable Channels in Aged 3xTg AD Mice
por: Li, Shuangtao, et al.
Publicado: (2023)

Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Javonillo, Dominic I., et al.
Publicado: (2022)

Abnormal whisker movements in the 3xTg‐AD mouse model of Alzheimer's disease
por: Simanaviciute, Ugne, et al.
Publicado: (2022)

Alterations in Retinal Signaling Across Age and Sex in 3xTg Alzheimer’s Disease Mice
por: Frame, Gabrielle, et al.
Publicado: (2022)

Genetic Knockdown of Brain-Derived Neurotrophic Factor in 3xTg-AD Mice Does Not Alter Aβ or Tau Pathology
por: Castello, Nicholas A., et al.
Publicado: (2012)

Proteomic analysis links alterations of bioenergetics, mitochondria-ER interactions and proteostasis in hippocampal astrocytes from 3xTg-AD mice
por: Dematteis, Giulia, et al.
Publicado: (2020)

Sex- and Neuropsychiatric-Dependent Circadian Alterations in Daily Voluntary Physical Activity Engagement and Patterns in Aged 3xTg-AD Mice
por: Alveal-Mellado, Daniel, et al.
Publicado: (2022)

Effects of the Novel IDO Inhibitor DWG-1036 on the Behavior of Male and Female 3xTg-AD Mice
por: Fertan, Emre, et al.
Publicado: (2019)

Inhibition of AMD-Like Pathology With a Neurotrophic Compound in Aged Rats and 3xTg-AD Mice
por: Liu, Yinghua, et al.
Publicado: (2019)

Differences in Immune-Related Genes Underlie Temporal and Regional Pathological Progression in 3xTg-AD Mice
por: Fernandes, Adelaide, et al.
Publicado: (2022)

The Effects of Physical Running on Dendritic Spines and Amyloid-beta Pathology in 3xTg-AD Male Mice
por: Xu, Benke, et al.
Publicado: (2022)

Attenuation of HECT-E3 ligase expression rescued memory deficits in 3xTg-AD mice
por: Suresh, Pavithra, et al.
Publicado: (2022)

β-Secretase 1’s Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice
por: Piedrahita, Diego, et al.
Publicado: (2016)

Progressive Vascular Abnormalities in the Aging 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Jullienne, Amandine, et al.
Publicado: (2022)

Sexual Dimorphism in the 3xTg-AD Mouse Model and Its Impact on Pre-Clinical Research
por: Dennison, Jessica L., et al.
Publicado: (2021)

Early Onset of Sex-Dependent Mitochondrial Deficits in the Cortex of 3xTg Alzheimer’s Mice
por: Djordjevic, Jelena, et al.
Publicado: (2020)

Spatial and Temporal Protein Modules Signatures Associated with Alzheimer Disease in 3xTg-AD Mice Are Restored by Early Ubiquinol Supplementation
por: Llanos-González, Emilio, et al.
Publicado: (2023)

Exercise and resveratrol increase fracture resistance in the 3xTg-AD mouse model of Alzheimer’s disease
por: Alkhouli, Mustafa F., et al.
Publicado: (2019)

Long-Term Dynamic Changes of NMDA Receptors Following an Excitotoxic Challenge
por: Granzotto, Alberto, et al.
Publicado: (2022)

Astrocyte Function Is Affected by Aging and Not Alzheimer’s Disease: A Preliminary Investigation in Hippocampi of 3xTg-AD Mice
por: Bronzuoli, Maria Rosanna, et al.
Publicado: (2019)

Age-dependent regulation of obesity and Alzheimer-related outcomes by hormone therapy in female 3xTg-AD mice
por: Christensen, Amy, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_et5ioeee131ft7av4t202dgqmf