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Arginase 2 deficiency reduces hyperoxia-mediated retinal neurodegeneration through the regulation of polyamine metabolism
Hyperoxia treatment has been known to induce neuronal and glial death in the developing central nervous system. Retinopathy of prematurity (ROP) is a devastating disease in premature infants and a major cause of childhood vision impairment. Studies indicate that, in addition to vascular injury, reti...
Autores principales: | Narayanan, S P, Xu, Z, Putluri, N, Sreekumar, A, Lemtalsi, T, Caldwell, R W, Caldwell, R B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944241/ https://www.ncbi.nlm.nih.gov/pubmed/24556690 http://dx.doi.org/10.1038/cddis.2014.23 |
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