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High-dose of vitamin C supplementation reduces amyloid plaque burden and ameliorates pathological changes in the brain of 5XFAD mice

Blood–brain barrier (BBB) breakdown and mitochondrial dysfunction have been implicated in the pathogenesis of Alzheimer's disease (AD), a neurodegenerative disease characterized by cognitive deficits and neuronal loss. Besides vitamin C being as one of the important antioxidants, recently, it h...

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Detalles Bibliográficos
Autores principales:	Kook, S-Y, Lee, K-M, Kim, Y, Cha, M-Y, Kang, S, Baik, S H, Lee, H, Park, R, Mook-Jung, I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944243/ https://www.ncbi.nlm.nih.gov/pubmed/24577081 http://dx.doi.org/10.1038/cddis.2014.26

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