TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer

Cisplatin is a cytotoxic platinum compound that triggers DNA crosslinking induced cell death, and is one of the reference drugs used in the treatment of several types of human cancers including gastric cancer. However, intrinsic or acquired drug resistance to cisplatin is very common, and leading to...

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Detalles Bibliográficos
Autores principales: Xu, W, Wang, S, Chen, Q, Zhang, Y, Ni, P, Wu, X, Zhang, J, Qiang, F, Li, A, Røe, O D, Xu, S, Wang, M, Zhang, R, Zhou, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944244/
https://www.ncbi.nlm.nih.gov/pubmed/24525731
http://dx.doi.org/10.1038/cddis.2014.27

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