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Expression of base excision repair key factors and miR17 in familial and sporadic breast cancer

Understanding of BRCA1/2 interaction with the base excision repair (BER) pathway could improve therapy based on ‘synthetic lethality', whose effectiveness is based on homologous recombination deficiency in cells lacking functional BRCA genes. However, poly (ADP-ribose) polymerase (PARP) inhibit...

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Detalles Bibliográficos
Autores principales:	De Summa, S, Pinto, R, Pilato, B, Sambiasi, D, Porcelli, L, Guida, G, Mattioli, E, Paradiso, A, Merla, G, Micale, L, De Nittis, P, Tommasi, S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944247/ https://www.ncbi.nlm.nih.gov/pubmed/24556691 http://dx.doi.org/10.1038/cddis.2014.30

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