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Survivin-2B promotes autophagy by accumulating IKK alpha in the nucleus of selenite-treated NB4 cells
Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others, and the mechanisms are unclear. In this report, we discovered that selenite, an antitumor agent, switched protective autophagy to apoptosis...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944251/ https://www.ncbi.nlm.nih.gov/pubmed/24556686 http://dx.doi.org/10.1038/cddis.2014.34 |