Phosphorylated AKT inhibits the apoptosis induced by DRAM-mediated mitophagy in hepatocellular carcinoma by preventing the translocation of DRAM to mitochondria

Increasing autophagy is beneficial for curing hepatocellular carcinoma (HCC). Damage-regulated autophagy modulator (DRAM) was recently reported to induce apoptosis by mediating autophagy. However, the effects of DRAM-mediated autophagy on apoptosis in HCC cells remain unclear. In this study, normal...

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Detalles Bibliográficos
Autores principales: Liu, K, Shi, Y, Guo, X H, Ouyang, Y B, Wang, S S, Liu, D J, Wang, A N, Li, N, Chen, D X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944266/
https://www.ncbi.nlm.nih.gov/pubmed/24556693
http://dx.doi.org/10.1038/cddis.2014.51

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