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PTEN regulates AMPA receptor-mediated cell viability in iPS-derived motor neurons

Excitatory transmission in the brain is commonly mediated by the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors. In amyotrophic lateral sclerosis (ALS), AMPA receptors allow cytotoxic levels of calcium into neurons, contributing to motor neuron injury. We have previously show...

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Detalles Bibliográficos
Autores principales:	Yang, D-J, Wang, X-L, Ismail, A, Ashman, C J, Valori, C F, Wang, G, Gao, S, Higginbottom, A, Ince, P G, Azzouz, M, Xu, J, Shaw, P J, Ning, K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944269/ https://www.ncbi.nlm.nih.gov/pubmed/24577094 http://dx.doi.org/10.1038/cddis.2014.55

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