Cargando…

MiRNA-210 modulates a nickel-induced cellular energy metabolism shift by repressing the iron–sulfur cluster assembly proteins ISCU1/2 in Neuro-2a cells

The cellular energy metabolism shift, characterized by the inhibition of oxidative phosphorylation (OXPHOS) and enhancement of glycolysis, is involved in nickel-induced neurotoxicity. MicroRNA-210 (miR-210) is regulated by hypoxia-inducible transcription factor-1α (HIF-1α) under hypoxic conditions a...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, M, Lu, Y, Xu, S, Mao, L, Zhang, L, Duan, W, Liu, C, Pi, H, Zhang, Y, Zhong, M, Yu, Z, Zhou, Z
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944272/ https://www.ncbi.nlm.nih.gov/pubmed/24577088 http://dx.doi.org/10.1038/cddis.2014.60

Ejemplares similares

Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron–sulfur deficiency and pulmonary hypertension
por: White, Kevin, et al.
Publicado: (2015)

MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU
por: Favaro, Elena, et al.
Publicado: (2010)

Solution Structure of the Iron−Sulfur Cluster Cochaperone HscB and Its Binding Surface for the Iron−Sulfur Assembly Scaffold Protein IscU
por: Füzéry, Anna K., et al.
Publicado: (2008)

Melatonin Antagonizes Nickel-Induced Aerobic Glycolysis by Blocking ROS-Mediated HIF-1α/miR210/ISCU Axis Activation
por: He, Mindi, et al.
Publicado: (2020)

The Role of CyaY in Iron Sulfur Cluster Assembly on the E. coli IscU Scaffold Protein
por: Iannuzzi, Clara, et al.
Publicado: (2011)

Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production
por: Ullmann, Pit, et al.
Publicado: (2016)

New insights into the pathology of pulmonary hypertension: implication of the miR-210/ISCU1/2/Fe-S axis
por: Tang, Haiyang, et al.
Publicado: (2015)

N-terminal tyrosine of ISCU2 triggers [2Fe-2S] cluster synthesis by ISCU2 dimerization
por: Freibert, Sven-A., et al.
Publicado: (2021)

Regulation of iron homeostasis by the p53-ISCU pathway
por: Funauchi, Yuki, et al.
Publicado: (2015)

miR-210 is a target of hypoxia-inducible factors 1 and 2 in renal cancer, regulates ISCU and correlates with good prognosis
por: McCormick, R I, et al.
Publicado: (2013)

The iron-sulfur cluster assembly genes iscS and iscU of Entamoeba histolytica were acquired by horizontal gene transfer
por: van der Giezen, Mark, et al.
Publicado: (2004)

FDX2 and ISCU Gene Variations Lead to Rhabdomyolysis With Distinct Severity and Iron Regulation
por: Montealegre, Sebastian, et al.
Publicado: (2022)

Ferredoxin, in conjunction with NADPH and ferredoxin-NADP reductase, transfers electrons to the IscS/IscU complex to promote iron–sulfur cluster assembly()
por: Yan, Robert, et al.
Publicado: (2015)

ISCU(M108I) and ISCU(D39V) Differ from Wild-Type ISCU in Their Failure To Form Cysteine Desulfurase Complexes Containing Both Frataxin and Ferredoxin
por: Cai, Kai, et al.
Publicado: (2018)

Mammalian Frataxin: An Essential Function for Cellular Viability through an Interaction with a Preformed ISCU/NFS1/ISD11 Iron-Sulfur Assembly Complex
por: Schmucker, Stéphane, et al.
Publicado: (2011)

The Complex Energy Landscape of the Protein IscU
por: Bothe, Jameson R., et al.
Publicado: (2015)

Interactions of iron-bound frataxin with ISCU and ferredoxin on the cysteine desulfurase complex leading to Fe-S cluster assembly
por: Cai, Kai, et al.
Publicado: (2018)

ISCU interacts with NFU1, and ISCU[4Fe-4S] transfers its Fe-S cluster to NFU1 leading to the production of holo-NFU1
por: Cai, Kai, et al.
Publicado: (2020)

Quercetin Antagonizes Glucose Fluctuation Induced Renal Injury by Inhibiting Aerobic Glycolysis via HIF-1α/miR-210/ISCU/FeS Pathway
por: Xu, Wei-long, et al.
Publicado: (2021)

Aberrant iron homeostasis, oxidative fiber enrichment, and activation of ketogenesis in muscle tissue of ISCU Myopathy patients
por: Crooks, Daniel R, et al.
Publicado: (2012)

MitoKATP regulating HIF/miR210/ISCU signaling axis and formation of a positive feedback loop in chronic hypoxia-induced PAH rat model
por: Lu, Yang, et al.
Publicado: (2017)

Monothiol Glutaredoxins Function in Storing and Transporting [Fe(2)S(2)] Clusters Assembled on IscU Scaffold Proteins
por: Shakamuri, Priyanka, et al.
Publicado: (2012)

Specialized Hsp70 Chaperone (HscA) Binds Preferentially to the Disordered Form, whereas J-protein (HscB) Binds Preferentially to the Structured Form of the Iron-Sulfur Cluster Scaffold Protein (IscU)
por: Kim, Jin Hae, et al.
Publicado: (2012)

miR-210 controls the evening phase of circadian locomotor rhythms through repression of Fasciclin 2
por: Niu, Ye, et al.
Publicado: (2019)

Human Mitochondrial Chaperone (mtHSP70) and Cysteine Desulfurase (NFS1) Bind Preferentially to the Disordered Conformation, Whereas Co-chaperone (HSC20) Binds to the Structured Conformation of the Iron-Sulfur Cluster Scaffold Protein (ISCU)
por: Cai, Kai, et al.
Publicado: (2013)

The role of zinc in the stability of the marginally stable IscU scaffold protein
por: Iannuzzi, Clara, et al.
Publicado: (2014)

NFU1, Iron-Sulfur Biogenesis, and Pulmonary Arterial Hypertension: A (Metabolic) Shift in Our Thinking
por: Culley, Miranda K., et al.
Publicado: (2020)

The role of miRNA-210 in pre-eclampsia development
por: Jaszczuk, Ilona, et al.
Publicado: (2022)

Cooperative redox and spin activity from three redox congeners of sulfur-bridged iron nitrosyl and nickel dithiolene complexes
por: Quiroz, Manuel, et al.
Publicado: (2022)

A novel de novo dominant mutation in ISCU associated with mitochondrial myopathy
por: Legati, Andrea, et al.
Publicado: (2017)

N(2) Binding to an Iron-Sulfur-Carbon Site
por: Čorić, Ilija, et al.
Publicado: (2015)

The shift of microbial communities and their roles in sulfur and iron cycling in a copper ore bioleaching system
por: Niu, Jiaojiao, et al.
Publicado: (2016)

Analytical Applications of Reactions of Iron(III) and Hexacyanoferrate(III) with 2,10-Disubstituted Phenothiazines
por: Puzanowska-Tarasiewicz, Helena, et al.
Publicado: (2009)

Clinically relevant HIF-1α-dependent metabolic reprogramming in oropharyngeal squamous cell carcinomas includes coordinated activation of CAIX and the miR-210/ISCU signaling axis, but not MCT1 and MCT4 upregulation
por: Sáenz-de-Santa-María, Inés, et al.
Publicado: (2017)

Characterization and Reconstitution of Human Lipoyl Synthase (LIAS) Supports ISCA2 and ISCU as Primary Cluster Donors and an Ordered Mechanism of Cluster Assembly
por: Hendricks, Amber L., et al.
Publicado: (2021)

The cold denaturation of IscU highlights structure–function dualism in marginally stable proteins
por: Yan, Robert, et al.
Publicado: (2018)

MiRNA-99a directly regulates AGO2 through translational repression in hepatocellular carcinoma
por: Zhang, J, et al.
Publicado: (2014)

Nickel Oxide Decorated Halloysite Nanotubes as Sulfur Host Materials for Lithium–Sulfur Batteries
por: Elibol, Meltem Karaismailoglu, et al.
Publicado: (2023)

Iron, neuro‐bioavailability and depression
por: Berthou, Christian, et al.
Publicado: (2021)

Upregulation of the miRNA-155, miRNA-210, and miRNA-20b in psoriasis patients and their relation to IL-17
por: El-Komy, Mohamed, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_oqafrna1kpshivjl1g5mvp0s7t