Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence

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Oncogenic stress-induced senescence (OIS) prevents the ability of oncogenic signals to induce tumorigenesis. It is now largely admitted that the mitogenic effect of oncogenes requires metabolic adaptations to respond to new energetic and bio constituent needs. Yet, whether glucose metabolism affects...

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Detalles Bibliográficos
Autores principales: Gitenay, D, Wiel, C, Lallet-Daher, H, Vindrieux, D, Aubert, S, Payen, L, Simonnet, H, Bernard, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944274/
https://www.ncbi.nlm.nih.gov/pubmed/24577087
http://dx.doi.org/10.1038/cddis.2014.63
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