Akt and mTOR mediate programmed necrosis in neurons

Necroptosis is a newly described form of regulated necrosis that contributes to neuronal death in experimental models of stroke and brain trauma. Although much work has been done elucidating initiating mechanisms, signaling events governing necroptosis remain largely unexplored. Akt is known to inhi...

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Detalles Bibliográficos
Autores principales: Liu, Q, Qiu, J, Liang, M, Golinski, J, van Leyen, K, Jung, J E, You, Z, Lo, E H, Degterev, A, Whalen, M J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944276/
https://www.ncbi.nlm.nih.gov/pubmed/24577082
http://dx.doi.org/10.1038/cddis.2014.69

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