Clinical Assessment of a Novel Recombinant Simian Adenovirus ChAdOx1 as a Vectored Vaccine Expressing Conserved Influenza A Antigens

Adenoviruses are potent vectors for inducing and boosting cellular immunity to encoded recombinant antigens. However, the widespread seroprevalence of neutralizing antibodies to common human adenovirus serotypes limits their use. Simian adenoviruses do not suffer from the same drawbacks. We have con...

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Detalles Bibliográficos
Autores principales: Antrobus, Richard D, Coughlan, Lynda, Berthoud, Tamara K, Dicks, Matthew D, Hill, Adrian VS, Lambe, Teresa, Gilbert, Sarah C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944330/
https://www.ncbi.nlm.nih.gov/pubmed/24374965
http://dx.doi.org/10.1038/mt.2013.284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944330/
https://www.ncbi.nlm.nih.gov/pubmed/24374965
http://dx.doi.org/10.1038/mt.2013.284

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