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A Three-day PGF(2α) Plus eCG-based Fixed-time AI Protocol Improves Fertility Compared with Spontaneous Estrus in Dairy Cows with Silent Ovulation
This study was designed to test the treatment with prostaglandin F(2α) (PGF(2α)) plus equine chorionic gonadotrophin (eCG) and GnRH 48 h later (PEG protocol) followed by fixed-time AI (FTAI) in dairy cows with silent ovulation (cows with a mature corpus luteum and no signs of estrus detected in the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Society for Reproduction and Development
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944361/ https://www.ncbi.nlm.nih.gov/pubmed/23698789 http://dx.doi.org/10.1262/jrd.2013-017 |
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author | GARCIA-ISPIERTO, Irina LÓPEZ-GATIUS, Fernando |
author_facet | GARCIA-ISPIERTO, Irina LÓPEZ-GATIUS, Fernando |
author_sort | GARCIA-ISPIERTO, Irina |
collection | PubMed |
description | This study was designed to test the treatment with prostaglandin F(2α) (PGF(2α)) plus equine chorionic gonadotrophin (eCG) and GnRH 48 h later (PEG protocol) followed by fixed-time AI (FTAI) in dairy cows with silent ovulation (cows with a mature corpus luteum and no signs of estrus detected in the preceding 21 days). In Experiment I, ovulation following the PEG protocol monitored in 24 cows with silent ovulation was recorded in 83% of the cows 36 h after GnRH treatment. In Experiment II, control cows were artificially inseminated during spontaneous estrus (4615 AI), while cows in the PEG group (1266 AI) were subjected to FTAI 24 h after GnRH treatment. Binary logistic regression revealed a significant effect of the interactions of treatment by season, by parity or by repeat breeding syndrome (>3 AI) on the conception rate. The conception rate was negatively affected by the warm season and age in controls but not in treated cows, whereas repeat breeder cows in the control and PEG groups were less (by a factor of 0.7) or more (by a factor of 1.5) likely to become pregnant, respectively, than the remaining animals. Moreover, the likelihood of twin pregnancy was lower in multiparous PEG (by a factor of 0.4) cows than in the remaining cows. This protocol, besides overcoming the negative effects of heat stress and age on the conception rate, increased fertility in repeat breeder cows compared with spontaneous estrus. Moreover, this treatment regimen reduced the twin pregnancy rate in multiparous cows. |
format | Online Article Text |
id | pubmed-3944361 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | The Society for Reproduction and Development |
record_format | MEDLINE/PubMed |
spelling | pubmed-39443612014-03-06 A Three-day PGF(2α) Plus eCG-based Fixed-time AI Protocol Improves Fertility Compared with Spontaneous Estrus in Dairy Cows with Silent Ovulation GARCIA-ISPIERTO, Irina LÓPEZ-GATIUS, Fernando J Reprod Dev Original Article This study was designed to test the treatment with prostaglandin F(2α) (PGF(2α)) plus equine chorionic gonadotrophin (eCG) and GnRH 48 h later (PEG protocol) followed by fixed-time AI (FTAI) in dairy cows with silent ovulation (cows with a mature corpus luteum and no signs of estrus detected in the preceding 21 days). In Experiment I, ovulation following the PEG protocol monitored in 24 cows with silent ovulation was recorded in 83% of the cows 36 h after GnRH treatment. In Experiment II, control cows were artificially inseminated during spontaneous estrus (4615 AI), while cows in the PEG group (1266 AI) were subjected to FTAI 24 h after GnRH treatment. Binary logistic regression revealed a significant effect of the interactions of treatment by season, by parity or by repeat breeding syndrome (>3 AI) on the conception rate. The conception rate was negatively affected by the warm season and age in controls but not in treated cows, whereas repeat breeder cows in the control and PEG groups were less (by a factor of 0.7) or more (by a factor of 1.5) likely to become pregnant, respectively, than the remaining animals. Moreover, the likelihood of twin pregnancy was lower in multiparous PEG (by a factor of 0.4) cows than in the remaining cows. This protocol, besides overcoming the negative effects of heat stress and age on the conception rate, increased fertility in repeat breeder cows compared with spontaneous estrus. Moreover, this treatment regimen reduced the twin pregnancy rate in multiparous cows. The Society for Reproduction and Development 2013-05-23 2013-08 /pmc/articles/PMC3944361/ /pubmed/23698789 http://dx.doi.org/10.1262/jrd.2013-017 Text en ©2013 Society for Reproduction and Development http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. |
spellingShingle | Original Article GARCIA-ISPIERTO, Irina LÓPEZ-GATIUS, Fernando A Three-day PGF(2α) Plus eCG-based Fixed-time AI Protocol Improves Fertility Compared with Spontaneous Estrus in Dairy Cows with Silent Ovulation |
title | A Three-day PGF(2α) Plus eCG-based Fixed-time AI Protocol Improves
Fertility Compared with Spontaneous Estrus in Dairy Cows with Silent
Ovulation |
title_full | A Three-day PGF(2α) Plus eCG-based Fixed-time AI Protocol Improves
Fertility Compared with Spontaneous Estrus in Dairy Cows with Silent
Ovulation |
title_fullStr | A Three-day PGF(2α) Plus eCG-based Fixed-time AI Protocol Improves
Fertility Compared with Spontaneous Estrus in Dairy Cows with Silent
Ovulation |
title_full_unstemmed | A Three-day PGF(2α) Plus eCG-based Fixed-time AI Protocol Improves
Fertility Compared with Spontaneous Estrus in Dairy Cows with Silent
Ovulation |
title_short | A Three-day PGF(2α) Plus eCG-based Fixed-time AI Protocol Improves
Fertility Compared with Spontaneous Estrus in Dairy Cows with Silent
Ovulation |
title_sort | three-day pgf(2α) plus ecg-based fixed-time ai protocol improves
fertility compared with spontaneous estrus in dairy cows with silent
ovulation |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944361/ https://www.ncbi.nlm.nih.gov/pubmed/23698789 http://dx.doi.org/10.1262/jrd.2013-017 |
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