Transactivation of bad by vorinostat-induced acetylated p53 enhances doxorubicin-induced cytotoxicity in cervical cancer cells

Vorinostat (VOR) has been reported to enhance the cytotoxic effects of doxorubicin (DOX) with fewer side effects because of the lower DOX dosage in breast cancer cells. In this study, we investigated the novel mechanism underlying the synergistic cytotoxic effects of VOR and DOX co-treatment in cerv...

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Detalles Bibliográficos
Autores principales: Lee, Sook-Jeong, Hwang, Sung-Ook, Noh, Eun Joo, Kim, Dong-Uk, Nam, Miyoung, Kim, Jong Hyeok, Nam, Joo Hyun, Hoe, Kwang-Lae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944441/
https://www.ncbi.nlm.nih.gov/pubmed/24525822
http://dx.doi.org/10.1038/emm.2013.149

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