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The role of the cytosolic HSP70 chaperone system in diseases caused by misfolding and aberrant trafficking of ion channels
Protein-folding diseases are an ongoing medical challenge. Many diseases within this group are genetically determined, and have no known cure. Among the examples in which the underlying cellular and molecular mechanisms are well understood are diseases driven by misfolding of transmembrane proteins...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Company of Biologists Limited
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944492/ https://www.ncbi.nlm.nih.gov/pubmed/24609033 http://dx.doi.org/10.1242/dmm.014001 |