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Glycoprotein folding and quality-control mechanisms in protein-folding diseases

Biosynthesis of proteins – from translation to folding to export – encompasses a complex set of events that are exquisitely regulated and scrutinized to ensure the functional quality of the end products. Cells have evolved to capitalize on multiple post-translational modifications in addition to pri...

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Detalles Bibliográficos
Autores principales: Ferris, Sean P., Kodali, Vamsi K., Kaufman, Randal J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944493/
https://www.ncbi.nlm.nih.gov/pubmed/24609034
http://dx.doi.org/10.1242/dmm.014589