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Glycoprotein folding and quality-control mechanisms in protein-folding diseases
Biosynthesis of proteins – from translation to folding to export – encompasses a complex set of events that are exquisitely regulated and scrutinized to ensure the functional quality of the end products. Cells have evolved to capitalize on multiple post-translational modifications in addition to pri...
Autores principales: | Ferris, Sean P., Kodali, Vamsi K., Kaufman, Randal J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944493/ https://www.ncbi.nlm.nih.gov/pubmed/24609034 http://dx.doi.org/10.1242/dmm.014589 |
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