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Early motor deficits in mouse disease models are reliably uncovered using an automated home-cage wheel-running system: a cross-laboratory validation

Deficits in motor function are debilitating features in disorders affecting neurological, neuromuscular and musculoskeletal systems. Although these disorders can vary greatly with respect to age of onset, symptomatic presentation, rate of progression and severity, the study of these disease models i...

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Detalles Bibliográficos
Autores principales: Mandillo, Silvia, Heise, Ines, Garbugino, Luciana, Tocchini-Valentini, Glauco P., Giuliani, Alessandro, Wells, Sara, Nolan, Patrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944499/
https://www.ncbi.nlm.nih.gov/pubmed/24423792
http://dx.doi.org/10.1242/dmm.013946