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Trabectedin and Plitidepsin: Drugs from the Sea that Strike the Tumor Microenvironment
The prevailing paradigm states that cancer cells acquire multiple genetic mutations in oncogenes or tumor suppressor genes whose respective activation/up-regulation or loss of function serve to impart aberrant properties, such as hyperproliferation or inhibition of cell death. However, a tumor is no...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944511/ https://www.ncbi.nlm.nih.gov/pubmed/24473171 http://dx.doi.org/10.3390/md12020719 |