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Harnessing the potential of bacterial ghost for the effective delivery of drugs and biotherapeutics

It seems to be a necessary need to develop an effective drug carrier system for targeted delivery of pharmaceuticals. Bacterial ghosts are emerging drug delivery platform that are capable of delivery of proteins, antigens, nucleic acids, and pharmaceuticals. Bacterial ghosts are generally produced b...

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Detalles Bibliográficos
Autores principales: Ganeshpurkar, Aditya, Ganeshpurkar, Ankit, Pandey, Vikas, Agnihotri, Abhishek, Bansal, Divya, Dubey, Nazneen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944611/
https://www.ncbi.nlm.nih.gov/pubmed/24678455
http://dx.doi.org/10.4103/2230-973X.127733
Descripción
Sumario:It seems to be a necessary need to develop an effective drug carrier system for targeted delivery of pharmaceuticals. Bacterial ghosts are emerging drug delivery platform that are capable of delivery of proteins, antigens, nucleic acids, and pharmaceuticals. Bacterial ghosts are generally produced by lysis of gram-negative bacteria. Pharmaceutically, these ghosts could be utilized to deliver proteins peptides, vaccines, drugs effectively. However, this technology is at initial stage and systematic studies are required to implement such system over humans.