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Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature

Mucormycosis is a rare but devastating infection. We present a case of fatal disseminated mucormycosis infection in a renal transplant patient. Uncontrolled diabetes mellitus and immunosuppression are the major predisposing factors to infection with Mucorales. Mucorales are angioinvasive and can inf...

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Detalles Bibliográficos
Autores principales: Hamdi, Tamim, Karthikeyan, Vanji, Alangaden, George J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944654/
https://www.ncbi.nlm.nih.gov/pubmed/24688793
http://dx.doi.org/10.1155/2014/950643
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author Hamdi, Tamim
Karthikeyan, Vanji
Alangaden, George J.
author_facet Hamdi, Tamim
Karthikeyan, Vanji
Alangaden, George J.
author_sort Hamdi, Tamim
collection PubMed
description Mucormycosis is a rare but devastating infection. We present a case of fatal disseminated mucormycosis infection in a renal transplant patient. Uncontrolled diabetes mellitus and immunosuppression are the major predisposing factors to infection with Mucorales. Mucorales are angioinvasive and can infect any organ system. Lungs are the predominant site of infection in solid organ transplant recipients. Prompt diagnosis is challenging and influences outcome. Treatment involves a combination of surgical and medical therapies. Amphotericin B remains the cornerstone in the medical management of mucormycosis, although other agents have been used. Newer agents are promising.
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spelling pubmed-39446542014-03-31 Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature Hamdi, Tamim Karthikeyan, Vanji Alangaden, George J. Int J Nephrol Review Article Mucormycosis is a rare but devastating infection. We present a case of fatal disseminated mucormycosis infection in a renal transplant patient. Uncontrolled diabetes mellitus and immunosuppression are the major predisposing factors to infection with Mucorales. Mucorales are angioinvasive and can infect any organ system. Lungs are the predominant site of infection in solid organ transplant recipients. Prompt diagnosis is challenging and influences outcome. Treatment involves a combination of surgical and medical therapies. Amphotericin B remains the cornerstone in the medical management of mucormycosis, although other agents have been used. Newer agents are promising. Hindawi Publishing Corporation 2014 2014-02-12 /pmc/articles/PMC3944654/ /pubmed/24688793 http://dx.doi.org/10.1155/2014/950643 Text en Copyright © 2014 Tamim Hamdi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Hamdi, Tamim
Karthikeyan, Vanji
Alangaden, George J.
Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature
title Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature
title_full Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature
title_fullStr Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature
title_full_unstemmed Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature
title_short Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature
title_sort mucormycosis in a renal transplant recipient: case report and comprehensive review of literature
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944654/
https://www.ncbi.nlm.nih.gov/pubmed/24688793
http://dx.doi.org/10.1155/2014/950643
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