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Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature
Mucormycosis is a rare but devastating infection. We present a case of fatal disseminated mucormycosis infection in a renal transplant patient. Uncontrolled diabetes mellitus and immunosuppression are the major predisposing factors to infection with Mucorales. Mucorales are angioinvasive and can inf...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944654/ https://www.ncbi.nlm.nih.gov/pubmed/24688793 http://dx.doi.org/10.1155/2014/950643 |
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author | Hamdi, Tamim Karthikeyan, Vanji Alangaden, George J. |
author_facet | Hamdi, Tamim Karthikeyan, Vanji Alangaden, George J. |
author_sort | Hamdi, Tamim |
collection | PubMed |
description | Mucormycosis is a rare but devastating infection. We present a case of fatal disseminated mucormycosis infection in a renal transplant patient. Uncontrolled diabetes mellitus and immunosuppression are the major predisposing factors to infection with Mucorales. Mucorales are angioinvasive and can infect any organ system. Lungs are the predominant site of infection in solid organ transplant recipients. Prompt diagnosis is challenging and influences outcome. Treatment involves a combination of surgical and medical therapies. Amphotericin B remains the cornerstone in the medical management of mucormycosis, although other agents have been used. Newer agents are promising. |
format | Online Article Text |
id | pubmed-3944654 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-39446542014-03-31 Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature Hamdi, Tamim Karthikeyan, Vanji Alangaden, George J. Int J Nephrol Review Article Mucormycosis is a rare but devastating infection. We present a case of fatal disseminated mucormycosis infection in a renal transplant patient. Uncontrolled diabetes mellitus and immunosuppression are the major predisposing factors to infection with Mucorales. Mucorales are angioinvasive and can infect any organ system. Lungs are the predominant site of infection in solid organ transplant recipients. Prompt diagnosis is challenging and influences outcome. Treatment involves a combination of surgical and medical therapies. Amphotericin B remains the cornerstone in the medical management of mucormycosis, although other agents have been used. Newer agents are promising. Hindawi Publishing Corporation 2014 2014-02-12 /pmc/articles/PMC3944654/ /pubmed/24688793 http://dx.doi.org/10.1155/2014/950643 Text en Copyright © 2014 Tamim Hamdi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Hamdi, Tamim Karthikeyan, Vanji Alangaden, George J. Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature |
title | Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature |
title_full | Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature |
title_fullStr | Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature |
title_full_unstemmed | Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature |
title_short | Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature |
title_sort | mucormycosis in a renal transplant recipient: case report and comprehensive review of literature |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944654/ https://www.ncbi.nlm.nih.gov/pubmed/24688793 http://dx.doi.org/10.1155/2014/950643 |
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