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Vorinostat in combination with lenalidomide and dexamethasone in patients with relapsed or refractory multiple myeloma
The addition of vorinostat to lenalidomide/dexamethasone represents a novel combination therapy in multiple myeloma (MM), informed by laboratory studies suggesting synergy. This was a phase I, multicenter, open-label, non-randomized, dose-escalating study in patients with relapsed or relapsed and re...
Autores principales: | Siegel, D S, Richardson, P, Dimopoulos, M, Moreau, P, Mitsiades, C, Weber, D, Houp, J, Gause, C, Vuocolo, S, Eid, J, Graef, T, Anderson, K C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944659/ https://www.ncbi.nlm.nih.gov/pubmed/24562384 http://dx.doi.org/10.1038/bcj.2014.1 |
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