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Dysferlin at transverse tubules regulates Ca(2+) homeostasis in skeletal muscle

The class of muscular dystrophies linked to the genetic ablation or mutation of dysferlin, including Limb Girdle Muscular Dystrophy 2B (LGMD2B) and Miyoshi Myopathy (MM), are late-onset degenerative diseases. In lieu of a genetic cure, treatments to prevent or slow the progression of dysferlinopathy...

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Detalles Bibliográficos
Autores principales: Kerr, Jaclyn P., Ward, Christopher W., Bloch, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944681/
https://www.ncbi.nlm.nih.gov/pubmed/24639655
http://dx.doi.org/10.3389/fphys.2014.00089