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Identification of the Catalytic Triad of Family S46 Exopeptidases, Closely Related to Clan PA Endopeptidases

The exopeptidases of family S46 are exceptional, as the closest homologs of these enzymes are the endopeptidases of clan PA. The three-dimensional structure of S46 enzymes is unknown and only one of the catalytic residues, the serine, has been identified. The catalytic histidine and aspartate residu...

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Detalles Bibliográficos
Autores principales: Suzuki, Yoshiyuki, Sakamoto, Yasumitsu, Tanaka, Nobutada, Okada, Hirofumi, Morikawa, Yasushi, Ogasawara, Wataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944710/
https://www.ncbi.nlm.nih.gov/pubmed/24598890
http://dx.doi.org/10.1038/srep04292

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