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Systems Biology-Based Identification of Mycobacterium tuberculosis Persistence Genes in Mouse Lungs

Identifying Mycobacterium tuberculosis persistence genes is important for developing novel drugs to shorten the duration of tuberculosis (TB) treatment. We developed computational algorithms that predict M. tuberculosis genes required for long-term survival in mouse lungs. As the input, we used high...

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Detalles Bibliográficos
Autores principales: Dutta, Noton K., Bandyopadhyay, Nirmalya, Veeramani, Balaji, Lamichhane, Gyanu, Karakousis, Petros C., Bader, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944818/
https://www.ncbi.nlm.nih.gov/pubmed/24549847
http://dx.doi.org/10.1128/mBio.01066-13