Mitochondrial DNA and Functional Investigations into the Radiosensitivity of Four Mouse Strains

We investigated whether genetic radiosensitivity-related changes in mtDNA/nDNA ratios are significant to mitochondrial function and if a material effect on mtDNA content and function exists. BALB/c (radiosensitive), C57BL/6 (radioresistant), and F1 hybrid mouse strains were exposed to total body irr...

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Detalles Bibliográficos
Autores principales: Zhang, Steven B., Maguire, David, Zhang, Mei, Tian, Yeping, Yang, Shanmin, Zhang, Amy, Casey-Sawicki, Katherine, Han, Deping, Ma, Jun, Yin, Liangjie, Guo, Yongson, Wang, Xiaohui, Chen, Chun, Litvinchuk, Alexandra, Zhang, Zhenhuan, Swarts, Steven, Vidyasagar, Sadasivan, Zhang, Lurong, Okunieff, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944901/
https://www.ncbi.nlm.nih.gov/pubmed/24688546
http://dx.doi.org/10.1155/2014/850460

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