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Characterization of Gp41 Polymorphisms in the Fusion Peptide Domain and T-20 (Enfuvirtide) Resistance-Associated Regions in Korean HIV-1 Isolates

HIV-1 gp41 is an envelope protein that plays an essential role in virus entry. The mutation of gp41 affects HIV-1 entry and susceptibility to the fusion inhibitor T-20. Therefore, we analyzed the natural polymorphism of gp41 of 163 HIV-1 isolates from T-20-naïve Koreans infected with HIV-1. This stu...

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Detalles Bibliográficos
Autores principales:	Jang, Dai-Ho, Yoon, Cheol-Hee, Choi, Byeong-Sun, Chung, Yoon-Seok, Kim, Hye-Young, Chi, Sung-Gil, Kim, Sung Soon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Academy of Medical Sciences 2014
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945146/ https://www.ncbi.nlm.nih.gov/pubmed/24616600 http://dx.doi.org/10.3346/jkms.2014.29.3.456

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