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Cancer Evolution Is Associated with Pervasive Positive Selection on Globally Expressed Genes

Cancer is an evolutionary process in which cells acquire new transformative, proliferative and metastatic capabilities. A full understanding of cancer requires learning the dynamics of the cancer evolutionary process. We present here a large-scale analysis of the dynamics of this evolutionary proces...

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Detalles Bibliográficos
Autores principales: Ostrow, Sheli L., Barshir, Ruth, DeGregori, James, Yeger-Lotem, Esti, Hershberg, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945297/
https://www.ncbi.nlm.nih.gov/pubmed/24603726
http://dx.doi.org/10.1371/journal.pgen.1004239