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Cancer Evolution Is Associated with Pervasive Positive Selection on Globally Expressed Genes
Cancer is an evolutionary process in which cells acquire new transformative, proliferative and metastatic capabilities. A full understanding of cancer requires learning the dynamics of the cancer evolutionary process. We present here a large-scale analysis of the dynamics of this evolutionary proces...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945297/ https://www.ncbi.nlm.nih.gov/pubmed/24603726 http://dx.doi.org/10.1371/journal.pgen.1004239 |