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Reduction of IL-17A Might Suppress the Th1 Response and Promote the Th2 Response by Boosting the Function of Treg Cells during Silica-Induced Inflammatory Response In Vitro

Silica inhalation can induce chronic lung inflammation and fibrosis. Upon silica stimulation, activated macrophages trigger the T-lymphocyte which can differentiate into many different types of Th cells, including the recently discovered Th17 cells. IL-17A, the typical Th17 cytokine, is reported in...

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Detalles Bibliográficos
Autores principales: Tang, Wen, Liu, Fangwei, Chen, Ying, Song, Laiyu, Dai, Wujing, Li, Chao, Weng, Dong, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945471/
https://www.ncbi.nlm.nih.gov/pubmed/24692850
http://dx.doi.org/10.1155/2014/570894