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An Epigenetic Signature in Peripheral Blood Associated with the Haplotype on 17q21.31, a Risk Factor for Neurodegenerative Tauopathy

Little is known about how changes in DNA methylation mediate risk for human diseases including dementia. Analysis of genome-wide methylation patterns in patients with two forms of tau-related dementia – progressive supranuclear palsy (PSP) and frontotemporal dementia (FTD) – revealed significant dif...

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Detalles Bibliográficos
Autores principales:	Li, Yun, Chen, Jason A., Sears, Renee L., Gao, Fuying, Klein, Eric D., Karydas, Anna, Geschwind, Michael D., Rosen, Howard J., Boxer, Adam L., Guo, Weilong, Pellegrini, Matteo, Horvath, Steve, Miller, Bruce L., Geschwind, Daniel H., Coppola, Giovanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945475/ https://www.ncbi.nlm.nih.gov/pubmed/24603599 http://dx.doi.org/10.1371/journal.pgen.1004211

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