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Targeting Extracellular DNA to Deliver IGF-1 to the Injured Heart
There is a great need for the development of therapeutic strategies that can target biomolecules to damaged myocardium. Necrosis of myocardium during a myocardial infarction (MI) is characterized by extracellular release of DNA, which can serve as a potential target for ischemic tissue. Hoechst, a h...
Autores principales: | Khan, Raffay S., Martinez, Mario D., Sy, Jay C., Pendergrass, Karl D., Che, Pao-lin, Brown, Milton E., Cabigas, E. Bernadette, Dasari, Madhuri, Murthy, Niren, Davis, Michael E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945489/ https://www.ncbi.nlm.nih.gov/pubmed/24604065 http://dx.doi.org/10.1038/srep04257 |
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