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Langerin+ Dermal DC, but not Langerhans cells, are required for effective CD8 mediated immune responses after skin scarification with Vaccinia Virus (VACV)
Skin scarification (s.s.) with Vaccinia virus (VACV) is essential for generation of an optimal protective T cell memory immune response. Dendritic Cells (DC), which are professional antigen presenting cells, are required for naïve T cell priming and activation. At least three subsets of skin residen...
Autores principales: | Seneschal, Julien, Jiang, Xiaodong, Kupper, Thomas S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945525/ https://www.ncbi.nlm.nih.gov/pubmed/24126845 http://dx.doi.org/10.1038/jid.2013.418 |
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