A highly specific q-RT-PCR assay to address the relevance of the JAK2WT and JAK2V617F expression levels and control genes in Ph-negative myeloproliferative neoplasms

In Ph− myeloproliferative neoplasms, the quantification of the JAK2V617F transcripts may provide some advantages over the DNA allele burden determination. We developed a q-RT-PCR to assess the JAK2WT and JAK2V617F mRNA expression in 105 cases (23 donors, 13 secondary polycythemia, 22 polycythemia ve...

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Detalles Bibliográficos
Autores principales: Fantasia, Francesca, Di Capua, Emma Nora, Cenfra, Natalia, Pessina, Gloria, Mecarocci, Sergio, Rago, Angela, Cotroneo, Ettore, Busanello, Anna, Equitani, Francesco, Lo-Coco, Francesco, Nervi, Clara, Cimino, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945640/
https://www.ncbi.nlm.nih.gov/pubmed/24173087
http://dx.doi.org/10.1007/s00277-013-1920-0

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