Naive CD4 T-cell activation identifies MS patients having rapid transition to progressive MS

OBJECTIVE: Our objective was to determine whether altered naive CD4 T-cell biology contributes to development of disease progression in secondary progressive multiple sclerosis (SPMS). METHODS: We compared the naive CD4 T-cell gene expression profiles of 19 patients with SPMS and 14 healthy controls...

Descripción completa

Detalles Bibliográficos
Autores principales: Zastepa, Evelyn, Fitz-Gerald, Leslie, Hallett, Michael, Antel, Jack, Bar-Or, Amit, Baranzini, Sergio, Lapierre, Yves, Haegert, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945666/
https://www.ncbi.nlm.nih.gov/pubmed/24453076
http://dx.doi.org/10.1212/WNL.0000000000000146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945666/
https://www.ncbi.nlm.nih.gov/pubmed/24453076
http://dx.doi.org/10.1212/WNL.0000000000000146

Ejemplares similares