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High calcium concentration in bones promotes bone metastasis in renal cell carcinomas expressing calcium-sensing receptor
BACKGROUND: The prognosis for renal cell carcinoma (RCC) is related to a high rate of metastasis, including 30% of bone metastasis. Characteristic for bone tissue is a high concentration of calcium ions. In this study, we show a promoting effect of an enhanced extracellular calcium concentration on...
Autores principales: | Joeckel, Elke, Haber, Tobias, Prawitt, Dirk, Junker, Kerstin, Hampel, Christian, Thüroff, Joachim W, Roos, Frederik C, Brenner, Walburgis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945739/ https://www.ncbi.nlm.nih.gov/pubmed/24576174 http://dx.doi.org/10.1186/1476-4598-13-42 |
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