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Considerations for clinical read alignment and mutational profiling using next-generation sequencing

Next-generation sequencing technologies are increasingly being applied in clinical settings, however the data are characterized by a range of platform-specific artifacts making downstream analysis problematic and error- prone. One major application of NGS is in the profiling of clinically relevant m...

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Detalles Bibliográficos
Autor principal:	Oliver, Gavin R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000Research 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945748/ https://www.ncbi.nlm.nih.gov/pubmed/24627757 http://dx.doi.org/10.12688/f1000research.1-2.v2

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