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Opening paths to novel analgesics: the role of potassium channels in chronic pain
Chronic pain is associated with abnormal excitability of the somatosensory system and remains poorly treated in the clinic. Potassium (K(+)) channels are crucial determinants of neuronal activity throughout the nervous system. Opening of these channels facilitates a hyperpolarizing K(+) efflux acros...
Autores principales: | Tsantoulas, Christoforos, McMahon, Stephen B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Applied Science Publishing
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945816/ https://www.ncbi.nlm.nih.gov/pubmed/24461875 http://dx.doi.org/10.1016/j.tins.2013.12.002 |
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